Document Type : Original Article

Authors

Department of Chemistry, Mangalore University, Mangalagangothri, India

Abstract

The medicinal properties shown by different plants are due to phytochemicals present in the plant. These phytochemicals are the most vital source for the treatment of various diseases. Different phytochemicals have an extensive range of activities, which help to enhance the immune system and give resistance to the body to protect against attack of harmful pathogens. It is well accepted fact that even areca plant seed is also a good source of phytochemicals and hence planned to examine the phytochemicals present in its different stages, that is, tender areca nut (TACN), mature areca nut (MACN) and dry areca nut (DACN). All the three stages of areca nut extract were examined for tannin, phenols, flavonoids, alcohols, acids, amines and nitro groups. They showed positive results for all the tests. Trace elements such as Cu, Fe, Zn, Cr, Ni, Pb are present in small amount when compared to Na and K, and are identified by Atomic Adsorption Spectroscopy. FTIR analysis revealed the presence of functional groups such as –OH. –NH, -CH, >C=O, >C=C<, >C-O-C and –NO groups in the areca nut extract. Extracts were investigated through GC-MS for identification of the chemical composition of extract, on comparison with results obtained from FTIR, and molecular mass nine, fourteen and five compounds were identified in TACN, MACN and DACN extracts, respectively.

Keywords

  1. Craig R Elevitch, 2006; “Traditional Trees of Pacific Islands: Their Culture, Environmentand USA” Permanent Agriculture Resources (PAR) publisher, USA; pp - 69-84.
  2. Preetee Jaiswal, Pradeep Kumar, V.K.Singh and D.K. Singh, 2011; “Areca catechu L. A Valuable Herbal Medicine Against Different Health Problems” Research Journal of Medicinal Plant; 5(2); 145-152.
  3. Bhandare A, Kshirsagar A, Vyawahare N, Hadambar A, Thorve S. 2010; Potential analgesic, anti-inflammatory and antioxidant activities of hydroalcoholic extract of Areca catechu L. nut. Food and Chemical Toxicology 48(12):3412-3417.
  4. Anthikat RRN, Michael A, Vageesh S, Balamurugan R, Ignacimuthu S. 2014 “The effect of Areca catechu L. extract on streptozotocin induced hyperglycemia in Wistar rats”. International Journal of Pharma and Bio Science; 5(4):316 – 21.
  5. Park YB, Jeon SM, Byun SJ, Kim HS, Choi MS. 2002; “Absorption of intestinal free cholesterol is lowered by supplementation of Areca catechu L. extract in rats”. Life Sciences, 70(16):1849-59.
  6. Jiang JH, Jung SY, Kim YC, Shin SR, Yu ST, Park H. 2009;”Antimalarial effects of Areca catechu L”. Korean J. Oriental Physiology and Pathology; 23(2): 494-8.
  7. Lee KK, Choi JD. 1999; “ The effects of Areca catechu L extract on anti-aging”. International J Cosmetic Science.;21(4), 285-95.
  8. Joshi M, Gaonkar K,Mangoankar S, Satarkar S. 2012; “Pharmacological investigation of Areca catechu extract forevaluation of learning, memory and behaviour in rats”. International Current Pharmaceutical Journal;1(6):128-132.
  9. Bhandare A, Kshirsagar A, Vyawahare N, Sharma P, Mohite R, 2011; “Evaluation of anti-migraine potential of Areca catechu to prevent nitroglycerin-induced delayed inflammation in rat meninges: possible involvement of NOS inhibition”. Journal of Ethnopharmacology; 136(1):267-70.
  10. Inokuchi J, Okabe H, Yamauchi T, Nagamatsu A,Nonaka G, et al. 1986; “Antihypertensive substance in seeds of Areca catechu L”. Life Sciences; 38(15): 1375-82.
  11. Dar A, Khatoon S, Rahman G, Rahman AU. 1997; “Anti-depressant activities of Areca catechu fruit extract”. Phytomedicine; 4(1):41-5.
  12. Lee JH, Chang SH, Park YS, Hes E, Lee HY, et al. 2004; “In-vitro and in-vivo anti-allergic actions of Areca semen”. J Pharmacy and Pharmacology;56(7):927-33.
  13. KeshavaBhat S, Mythri S, Ashwin D. 2016; “Anthelmintic property of areca nut (Areca catechu L.): A review”. Indian Journal of  Areca nut Spices and Medicinal Plants; 18(2), 20-7.
  14. Sazwi NN, Nalina T, Abdul Rahim ZH. 2013; “Antioxidant and cytoprotective activities of Piper betle, Areca catechu, Uncarria gambir and betel quid with and without calcium hydroxide”. BMC Complementary and Alternative Medicine; 13:351.
  15. Keshava Bhat  Sarpangala, Mythri Sarpangala, Ashwini Devasya, 2017; “Antimicrobial Properties of Areca nut, Areca catechu L; A Review” International. Journal of .Research in Ayurveda and  Pharmacy; 8(3); 8-12.
  16. Kumari HL, Sirsi M, Bhargava MK. 1974; “Inhibitory activity of Areca catechu on the development of mouse skin tumours induced by the chemical carcinogen 3.4, benzpyrene”. J Plantation Crop; 2(1):23-9.
  17. M. Turoti; E. Bello ; 2013; “World Rural Obs.”, 5; 64
  18. Petra Marschner, 2012; “Marschner’s Mineral Nutrition of Higher Plants”  Academic Press; California; 3rd edition; pp- 135-250.
  19. Michael.I.Goran; Luc Tappy; Kim-Ann Le; 2014; “Dietary Sugars and Health”, CRC Press, Newyork; pp- 62.
  20. John Griffith Vaughan;  2003; “The Oxford Book of Health Food : A Comprehensive Guide to Natural Remedies”, Oxford University Press, Newyork;  pp-61.
  21. Marion Eugene Ensmiger; Audrey H. Ensminger, 1993;“Food and Nutrition Encyclopedia” CRC Press Newyork; 2nd edition volume 1; pp- 719.
  22. Mark Crocker, 2010; “Thermochemical Conservation of Biomass of Liquid Fuels and Chemicals”, Royal Society of Chemistry, Cambridge; pp-347-348.
  23. L. Segal.J; J. Creely; A.E. Martin; Jr.C. M. Conrad; 1959; “An Empirical Method for Estimating the Degree of Crystallinity of Native Cellulose Using the X-ray Diffractometer”  Textile Research Journal; 29(10); 789-794.
  24. Tomy. J. Gutierrez; 2018; “Polymer for Food Applications” Springer, Switzerland; pp- 538.
  25. Fem D.S. Marquis; 2017; “Proceedings of the 8th Pacific Rim International Conference on Advanced Materials and Processing (PRICM-8)- The Minerals, Metals and Materials series” Springer, Switzerland; pp-  3243.
  26. Cury Suryanarayana; 2004; “Mechanical Alloying and Milling” CRC Press, Newyork; pp- 110-113.
  27. Dewan S.K, 2010; “Organic Spectroscopy: (NMR, IR, Mass and UV)”  CBS Publisher and Distributor Pvt. Ltd; first edition; pp- 400-463.
  28. Deepa Santhanakrishnan; Supriya N. Shankar; Bangaru Chandrasekaran, 2014;  “ Studies on Photochemistry, Spectroscopic Characterization and Anti-bacterial Efficacy of Salicornia brachiata”  International journal of Pharmacy and Pharmaceutical Sciences; 6(6); 430-432.
  29. Galen W. Ewing; 1985; “Instrumental Method of Chemical Analysis”, Mc Graw- Hill Book Co, Singapore; pp- 367-369.
  30. Donald T Sawyer; William R. Heinman; Janice M. Beebe; 1984; “Chemistry Equipment’s for Instrumental Methods” John Wiley and Sons, Newyork; pp- 327.
  31. Dr. Supriya S. Mahajan; 2010; “Instrumental Method of Analysis”, Prakashan Private Limited, Mumbai; pp- 235-240.
  32. Robert B Raffa,  2014; “Kartom and Mitragynines; The Chemistry and Pharmacology of Opioids from Non-Opinum Source” CRC press New york; pp- 197.
  33. Ojochenemi. E Yakubu, Olawale otitoju and Joshua onwuka, 2017; “ Gass chromatography- Mass spectroscopy (GC-MS) analysis of Aqueous Extract of Daniellia Oliveri Stem Bark” Pharmaceutical Analytical Acta; 8(11).
  34.  Sirigiri chandrakala and Kandru Ammani,  2017; “GC-MS analysis of Biologically active compounds in Canthium parviflorum Lam. Leaf and callus extract” Internatinal jornal of Chem Tech research; 10(6); pp- 1038-1058.
  35. Sanjay K Sharma; 2011; “ Green Corrosion Chemistry and Engineering Opportunities and Challenges” John Willey and sons, Germany; pp-96.
  36. Lawrence A Schachner, Ronald C Hansen, 2011; “ Pediatric Dermatology E-book” 4th edition; Elsevier Health Science publication, New york; pp-177.
  37. David S.Seigler, 1998; “Plant secondary Metabolism” Springer Science and Business Media, New york; pp- 617-621.
  38. Mohamad Jawad Kadham; Ghaidaa Jihadi Mohamed and Imad Hadi Hameed, 2016; “Invitro Antibacterial, Antifungal and Phytochemical Analysis of Methanolic extract of fruit Cassia fistula” Oriental Journal of chemistry; 32(13); pp- 1329-1346.
  39.  Eula Bingham, Barbara Cohrssen; 2012; “Patty’s Toxicology” John Wiley and sons, New Jersey; Volume 6; pp-584.
  40. Chukwunonye M; Ojinnaka kelechi I and Marycolatte N Ezediokpu; 2015; “The Chemical Constituents and Bioactivity of seed (Fruit) Extract of Buchholzia Coriacea Engler (capparaceae)” Journal of applied science and Environment; 19(4); pp- 795-801.
  41. Mustaph N.Abubakar and Runner R.T.Majinda; 2016 “GC-MS Analysis and Preliminary Antimicrobial Activity of Albizia adianthifolia (Schumach) and Peterocarpus angolensis (DC)” Journal of Medicine 3 (3).
  42. Victor R Preedy; Ronald Ross Watson, 2014; “The Mediterranean Diet: An Evidence- Based Approach” Academic Press, London; pp-281-289.
  43. Egui zhu; Sabo Sambath, 2012; “Information Technology and Agricultural Engineering Volume 134 of  Advances in Intelligent and Soft Computing” Springer Science and Business Media, New york; pp-650.
  44.  Oskars Purmalis; Dmitrijs Porsnovs; Maris Klavins, 2011; “Differential Thermal analysis of Peat and Peat Humic Acids”   Scientific Journal of Riga Technical University Materials Science and Applied Chemistry; Volume 24; pp- 89-94.
  45. Ashok Pandey, 2008; “Hand book of Plant- Based Biofuels” CRC Press, Boca Raton; pp-122.
  46. A.V. Bridgwater, 2013; “Advances in Thermochemical Biomass Conversion” Springer Science and Business Media, Dordrecht; pp- 774.
  47. Darrel.D.Nicholas, 1982; “Wood Deterioration and its prevention by Preservative Treatments: Degradation and Protection of Woods” Syracuse university Press, New york; pp- 310.
  48. Jitendra K. Pandey; Hitoshi Takagi; Antanio Nario Nakagaito; Hyun-Joong Kim, 2014; “Hand Book of Polymer Nano composites, Processing, Performance and Applications: Volume C: Polymer Nano composites of Cellulose Nano particles”, Springer, Newyork; pp-74-77.